Cardiovascular Disease Risk Factors In Youth With Diabetes Mellitus

  • The rates of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are increasing in youth.
  • Two- to 10-fold increases in rates of coronary heart disease and death resulting from coronary heart disease in T1DM were reported in multiple studies involving adults.
  • One approach to cardiovascular disease risk reduction in diabetes mellitus uses the A, B, C approach. In addition to glucose control (HbA1c, or A), blood pressure (BP or B), and cholesterol (C) management are emphasized.
  • Modifiable CVD risk factors for people with diabetes mellitus include obesity, IR, inflammation, oxidative stress, kidney disease, and lifestyle factors such as smoking, diet, exercise, psychosocial stress, depression, and sleep.
  • Non-modifiable CVD risk factors include genetics, family history, diabetes mellitus duration, and racial/ethnic disparities.
  • More clinical trial information is needed to better understand pharmacological treatment and prevention of risk factors.

    Read the full article in Circulation
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Posted by Stacy AHA Science on Aug 28, 2014 4:49 PM America/Chicago