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AHA Science News

2014 ACC/AHA/AATS/PCNA/SCAI/STS Focused Update of the Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease

  • SIHD focused update for diagnosis, treatment, and revascularization
  • New section addressing invasive testing and the role of coronary angiography for diagnosis
  • Consensus from multiple specialties

    Read the full article in Circulation
    [published online ahead of print July 28, 2014. Circulation. doi: 10.1161/CIR.0000000000000095.

Posted by Stacy AHA Science on Jul 28, 2014 3:00 PM CDT

Evidence for Stroke Family Caregiver and Dyad Interventions

Journal Cover
  • Stroke is a leading cause of severe, long-term disability, and most stroke survivors are cared for by family members within the home.
  • Stress of the caregiver becomes a leading cause of institutionalization of the stroke survivor; institutionalization results in increased healthcare system costs.
  • This paper is a systematic review of evidence targeting stroke caregivers and their dyads.  The goal is to unders.

    Read the full article in Stroke
    [published online ahead of print July 17, 2014] Stroke. doi: 10.1161/STR.0000000000000033.
Posted by Stacy AHA Science on Jul 17, 2014 4:36 PM CDT
AHA Science News

Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States

  • Hispanics are the largest minority ethnic group in the United States, and their health is vital to the public health of the nation and to achieving the AHA’s 2020 goals.
  • This statement describes the cardiovascular disease epidemiology, related personal beliefs, the social and health issues of US Hispanics, and identifies potential prevention and treatment opportunities.
  • Recommendations specific to 9 domains are presented to support the development of these culturally tailored and targeted approaches.

    Read the full article in Circulation
    Circulation. doi: 10.1161/CIR.0000000000000071.
Posted by Stacy AHA Science on Jul 14, 2014 5:06 PM CDT
AHA Science News

Emergence of the Primary Pediatric Stroke Center: Impact of the Thrombolysis in Pediatric Stroke Trial
Timothy J. Bernard, Michael J. Rivkin, Kelley Scholz, Gabrielle deVeber, Adam Kirton, Joan Cox Gill, Anthony K. Chan, Collin A. Hovinga, Rebecca N. Ichord, James C. Grotta, Lori C. Jordan, Susan Benedict, Neil R. Friedman, Michael M. Dowling, Jorina Elbers, Marcela Torres, Sally Sultan, Dana D. Cummings, Eric F. Grabowski, Hugh J. McMillan, Lauren A. Beslow, Catherine Amlie-Lefond, on behalf of the Thrombolysis in Pediatric Stroke Study
Stroke. 2014; STROKEAHA.114.004919 Published online before print June 10, 2014, doi: 10.1161/?STROKEAHA.114.004919

Posted by Stacy AHA Science on Jun 27, 2014 11:17 AM CDT
AHA Science News

Hypertension disorders in pregnancy include gestational hypertension, pre-eclampsia, eclampsia, and chronic hypertension.  These disorders have been shown to complicate between 6% and 20% of pregnancies. Risk factors for hypertensive disorders include increasing maternal age and greater body mass index at the time of pregnancy. These disorders have been shown to enhance the likelihood of small for gestational age offspring, preterm births, and infants with low birth weight. Detection and treatment of hypertension are essential to reduce the risk of the sequelae related to hypertension in pregnancy.  Macdonald-Wallis et al demonstrate the effects of hypertension on offspring in this large prospective study.

Associations of Blood Pressure Change in Pregnancy With Fetal Growth and Gestational Age at Delivery: Findings From a Prospective Cohort
Macdonald-Wallis C, Tilling K, Fraser A, Scott M, Lawlor DA. Hypertension. Originally published May 12, 2014. doi: 10.1161/HYPERTENSIONAHA.113.02766

 High blood pressure during pregnancy is associated with reduction of intrauterine growth and also with preterm births.  These associations have not been well studied.  This study looked at over 9600 women and children to understand these relationships better.  This study found that higher systolic BPs (not diastolic) at the study’s baseline (8 weeks gestation) and increase in systolic and diastolic blood pressure within 18-36 weeks of gestation were associated with lower birth weights and smaller for gestational age offspring. Greater increases in blood pressure, from the 18-week nadir, are related to decreased fetal growth and shorter gestation time, even in women whose blood pressure does not cross the parameters for hypertensive disorders of pregnancy.  This is the first prospective study to examine hypertension in relation to outcome of offspring.
Posted by Stacy AHA Science on Jun 25, 2014 2:58 PM CDT
AHA Science News

scinews-banner_Elevated Blood Pressure in Children

High blood pressure is a major risk factor for cardiovascular disease and stroke. Data indicate that the prevalence of high blood pressure in children and adolescents has been on the rise since 1988, with African-American and Hispanic youths at greater risk. This is especially concerning since children with elevated blood pressure are more likely to have hypertension as adults. Further, increased atherosclerosis at higher blood pressure levels has been observed in the young. The following studies investigate the development, evaluation, and treatment of elevated blood pressure in pediatric populations.

Posted by Stacy AHA Science on Jun 17, 2014 4:33 PM CDT
AHA Science News

Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic Heart Disease

  • Under-treatment and under-testing in women lead to increased complications and to higher case fatalities.
  • Atherosclerotic coronary artery (CAD) disease continues to be underrecognized and underdiagnosed in women, contributing to the high mortality
  • of CAD in women. 
  • This statement provides modern evidence to assist in identifying the appropriate female candidates for diagnostic testing.

    Read the full article in Circulation
    [published online ahead of print June 16, 2014]. Circulation. doi: 10.1161/CIR.0000000000000061.
Posted by Stacy AHA Science on Jun 16, 2014 8:53 PM CDT
AHA Science News

Atherosclerosis is the underlying cause of the majority of clinical cardiovascular events. The fundamental role of epigenetics in the development of atherosclerosis has become increasingly recognized. The following studies investigate novel mechanisms by which epigenetic modifications influence disease progression.

Posted by Stacy AHA Science on Jun 13, 2014 4:23 PM CDT
AHA Science News

  • This paper provides an overview of the evidence on physical activity and exercise for stroke survivors.
  • Current evidence suggests that stroke survivors have physical deconditioning and lead inactive lifestyles.

    Read the full article in Stroke
    [published online ahead of print May 20, 2014]. Stroke. doi: 10.1161/STR.0000000000000022.
Posted by Stacy AHA Science on May 20, 2014 3:16 PM CDT
AHA Science News

Evolution of “The Guideline Advantage”: Lessons Learned From the Front Lines of Outpatient Performance Measurement

  • Launched in 2011, The Guideline Advantage (TGA) is a jointly operated program by the American Heart Association, the American Cancer Society, and the American Diabetes Association to promote consistent use of evidence-based practice guidelines through existing healthcare technology in the outpatient setting.
  • The 3 organizations have been working closely ever since to increase public awareness about healthy lifestyles, support policies that increase funding for and access to prevention programs and research, and increase the focus on prevention among healthcare providers.
  • Enhancement of the ability of providers and researchers to leverage the wealth of data being collected for quality improvement and population management will ultimately improve the health of patients across the country.
  • The lessons learned from the implementation and evolution of TGA can inform the growing need for technology platforms that support data aggregation and analytics tied to quality improvement at the patient-population level while facilitating various payment models in meaningful and immediate ways.

    Read the full article in Circulation: Cardiovascular Quality and Outcomes
    [published online ahead of print April 30, 2014]. Circ Cardiovasc Qual Outcomes. doi: 10.1161/HCQ.0000000000000003.
Posted by Stacy AHA Science on May 14, 2014 3:00 PM CDT
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