Cardiovascular Disease Risk Factors In Youth With Diabetes Mellitus
The rates of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are increasing in youth.
Two- to 10-fold increases in rates of coronary heart disease and death resulting from coronary heart disease in T1DM were reported in multiple studies involving adults.
One approach to cardiovascular disease risk reduction in diabetes mellitus uses the A, B, C approach. In addition to glucose control (HbA1c, or A), blood pressure (BP or B), and cholesterol (C) management are emphasized.
Modifiable CVD risk factors for people with diabetes mellitus include obesity, IR, inflammation, oxidative stress, kidney disease, and lifestyle factors such as smoking, diet, exercise, psychosocial stress, depression, and sleep.
Non-modifiable CVD risk factors include genetics, family history, diabetes mellitus duration, and racial/ethnic disparities.
More clinical trial information is needed to better understand pharmacological treatment and prevention of risk factors.