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Depression, A Risk Factor For Poor ACS Prognosis
Although the association between depression and increased morbidity and mortality has been well documented in a variety of cardiac populations, depression has not yet achieved formal recognition as a risk factor for poor prognosis in patients with acute coronary syndrome.
A systematic literature review on depression and adverse medical outcomes after acute coronary syndrome was conducted that included all-cause mortality, cardiac mortality, and composite outcomes for mortality and nonfatal events.
Based on available evidence, recommendation is made to elevate depression to the status of a risk factor for patients with acute coronary syndrome.