Cholesterol Loading Reprograms The MicroRNA-143/145–Myocardin Axis To Convert Aortic Smooth Muscle Cells To A Dysfunctional Macrophage-Like Phenotype



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Arteriosclerosis, Thrombosis,
and Vascular Biology

ATVB March 2015 cov larger 


Editors' Pick for March

From the editors:
This article demonstrates that cholesterol loading of vascular smooth muscle cells results in its convertion to macrophage-appearing state through a miR-143/145-myocardin-serum response factor related mechanism.

Cholesterol Loading Reprograms the MicroRNA-143/145–Myocardin Axis to Convert Aortic Smooth Muscle Cells to a Dysfunctional Macrophage-Like Phenotype
Abstract | Free Full Text | PDF | Data Supplement

Video: Highlights of ATVB Journal 2014 with Editor-in-Chief Alan Daugherty, PhD, DSc, FAHA 


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Posted by Stacey SIMS on Feb 27, 2015 5:44 PM America/Chicago

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